Invention Grant
- Patent Title: 1,2-substituted cyclopentanes as orexin receptor antagonists
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Application No.: US15120048Application Date: 2015-02-19
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Publication No.: US10011588B2Publication Date: 2018-07-03
- Inventor: Charlotte Fieldhouse , Angela Glen , Stephanie Maine , Tatsuhiko Fujimoto , John Stephen Robinson
- Applicant: Takeda Pharmaceutical Company Limited
- Applicant Address: JP Osaka-Shi, Osaka
- Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
- Current Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
- Current Assignee Address: JP Osaka-Shi, Osaka
- Agency: Dtward, PC
- Agent Donna T. Ward; Anna E. Stanford
- Priority: EP14156011 20140220
- International Application: PCT/GB2015/050480 WO 20150219
- International Announcement: WO2015/124932 WO 20150827
- Main IPC: C07D403/12
- IPC: C07D403/12 ; C07D213/74 ; C07D239/42 ; A61K31/44 ; A61K31/4439 ; A61K31/4965 ; A61K31/497 ; A61K31/505 ; A61K31/506 ; A61K45/06 ; C07D241/20 ; C07D401/12 ; C07D413/12 ; C07D401/14
Abstract:
The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, (I) wherein L, X, Ra, Rb, R1, R2 and R3 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
Public/Granted literature
- US20170066744A1 1,2-SUBSTITUTED CYCLOPENTANES AS OREXIN RECEPTOR ANTAGONISTS Public/Granted day:2017-03-09
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