A carbon dioxide separation and recovery system includes an adsorption tower, a regeneration tower, and a drying tower. The adsorption tower causes a target gas to contact an adsorbent to adsorb carbon dioxide contained in the target gas to the adsorbent. The regeneration tower causes a normal-pressure wet gas which is a gas mixture of the carbon dioxide and steam to contact the adsorbent having adsorbed the carbon dioxide to desorb the carbon dioxide from the adsorbent. The drying tower dries the adsorbent. In addition, the carbon dioxide separation and recovery system includes a compressor that compresses the carbon dioxide, and an ejector that expands the carbon dioxide discharged from the compressor while suctioning negative-pressure steam, to generate the wet gas.