The invention provides a high-purity quartz sand preparation process. The high-purity quartz sand preparation process comprises the steps of carrying out artificial mineral processing according to themass of quartz ore raw materials by breaking through a traditional quartz sand process mode; washing the quartz ore raw materials with flowing water; crushing the quartz ore raw materials into quartzore particles by using a cone crusher; heating the quartz ore particles and then cooling the same; filtering out the quartz ore particles from water and then air-drying the quartz ore particles; grinding the quartz ore particles into quartz coarse sand, screening out the quartz coarse sand of which the grain size is smaller than the set mesh number in a process of grinding quartz ore particles, and adding fine quartz ground sand in the quartz coarse sand and grinding the mixture; filtering out quartz ground sand, impurities and quartz sand with over-small grain size in the ground quartz coarse sand; carrying out pulse dust removal on the filtered quartz coarse sand to obtain quartz coarse sand without dust; carrying out magnetic separation on the quartz coarse sand without dust; carryingout color sorting on the magnetically separated quartz coarse sand by using a color sorting machine; and carrying out microwave irradiation on the magnetically separated quartz coarse sand.