The invention discloses an AI application system for an intelligent endoscope operation. The system comprises an endoscope device layer, a connection end of the endoscope device layer is provided witha data transmission unit, and a connection end of the data transmission unit is provided with a cloud computing layer; the endoscope device layer comprises an endoscope control unit, an endoscope camera, an endoscope display and a device number storage unit; the cloud computing layer comprises a cloud computing server, a timer, a cloud memory and an image identification unit; and the data transmission unit is used for data transmission between the endoscope device layer and the cloud computing layer. Collected images are compared via the image identification unit, a doctor is helped to determine condition of a patient, compared with artificial determination, a determination result is more accurate, the operation difficulty of the doctor is reduced, and adverse influence of misjudgment ofthe doctor on the treating process of the patient can be avoided.