The invention discloses an inertial stick-slip type cross-scale motion platform, the platform comprises a protection base and a motion mechanism arranged in the protection base, wherein the motion mechanism comprises a piezoelectric ceramic, a motion assembly and an inertia assembly, the motion assembly comprises a motion transmission component and a motion output component connected to the motiontransmission component; the inertia assembly comprises an inertia transmission component and a friction component connected to the inertia transmission component; the piezoelectric ceramic is provided with a first end and a second end which are arranged opposite to each other, the first end is in contact with the motion transmission component, the second end is in contact with the inertia transmission component, the motion transmission component and the inertia transmission component are connected by means of an elastic deformation component, and a cross ball guide rail used for guiding the motion output component is arranged on the protection base, and the friction force between the motion output component and the cross ball guide rail is less than the friction force generated by the contact between the friction component and the protection base. The inertial stick-slip type cross-scale motion platform is simple in structure, simple in manufacturing process, and low in manufacturingcost, and can realize cross-scale precise positioning.