The invention provides a mural painting with a mosquito repelling function. Through a wormwood herb mosquito repelling layer, a waterproof layer, a fireproof layer and a painting layer which are sequentially arranged on a substrate, a decorative painting provided by the invention not only has a decoration function, but also is capable of slowly releasing a gas for repelling mosquitoes, and the mural painting is used for repelling the mosquitoes in a room and simultaneously has the decoration function.