The invention belongs to a molybdenum alloy film plating technology and particularly relates to a nickel plating technology of a molybdenum alloy substrate. The nickel plating technology comprises thefollowing steps that 1, a molybdenum sheet is put into a cleaning tank for chemical cleaning, and is aired; 2, the molybdenum sheet after being aired is subjected to plasma cleaning, and the purifiedmolybdenum sheet is obtained; 3, after being subjected to vacuum heating, the molybdenum sheet is subjected to preplating treatment and then is cooled to obtain the molybdenum sheet after preplating;4, the molybdenum sheet after the preplating is subjected to heat treatment, and after the heat treatment is completed, the molybdenum sheet with a preplating film is obtained; and 5, the molybdenumsheet with the preplating film is subjected to the vacuum heating and then is subjected to nickel plating treatment, and a nickel plating molybdenum alloy substrate is obtained. The problems that chemical plating is severe in pollution and poor in stability in the prior art are solved, a good green film plating method is formed by a vacuum plating method, and any harmful substances are not produced.