The invention provides a hoisting method of a large-section prefabricated part. The hoisting method of the large-section prefabricated part comprises the steps of firstly, arranging a plurality of supporting point positions corresponding to a lowering position of a corresponding prefabricated part, arranging a hydraulic support device on each supporting point position, and simultaneously connecting the hydraulic support devices to a control system; when utilizing a hoisting device for lowering the large-section prefabricated part, firstly enabling one hydraulic support device to be loaded, andstopping lowering the prefabricated part when a pressure stressed by the hydraulic support device reaches to a set value; adjusting oil pressures of other hydraulic support devices, and enabling thehydraulic support devices on the other supporting point positions to reach to a same stress state; and simultaneously or sequentially pressurizing the hydraulic support devices, utilizing the hydraulic support devices for supporting the prefabricated part, and stably transferring the prefabricated part to the hydraulic support devices. The hoisting method provided by the invention is simple in principle and convenient to operate, and uncertainty brought by manual operation is avoided on the premise of saving manpower.