An anti-corrosion structure and a fuel cell employing the same are provided. The anti-corrosion structure includes an aluminum layer, a first anti-corrosion layer, and an intermediate layer disposed between the aluminum layer and the first anti-corrosion layer. In particular, the first anti-corrosion layer can be a nickel-tin-containing alloy layer, and the intermediate layer can be a nickel-tin-aluminum-containing alloy layer.