The invention provides a flame-retardant antibacterial ABS (Acrylonitrile Butadiene Styrene) complex substance as well as a preparation method and application thereof. The flame-retardant antibacterial ABS complex substance is prepared from the following components in parts by weight: 73-83.5 parts of ABS, 10-20 parts of brominated flame-retardant agent, 1-5 parts of flame-retardant synergist, 1-10 parts of bonding modifier, 0.1-0.5 parts of bonding and modifying synergist, 0.5-2 parts of antibacterial agent and 0.1-3 parts of additive. The flame-retardant antibacterial ABS complex provided bythe invention is excellent in mechanical property and binding strength and high in stability. The preparation method is simple and easy in implementation and processing and is very suitable for promotion and application in the field (such as storage batteries) of gum sealing.