The invention discloses a method for designing process conditions of Fischer-Tropsch synthetic wax. The method is characterized in that the key factors that affect the synthesis process are extractedaccording to single-factor experimental results, and the influence laws of the key factors and synergistic and square terms thereof on the synthesis process are then obtained by means of central composite experiments and by using a secondary regression method study, and the synthesis process parameters are optimized. When an experiment is carried out under the operation conditions, higher intermediate distillate oil yield can be obtained.