The invention discloses a rapid detection reagent for heavy metal lead. The rapid detection reagent comprises a reagent A and a reagent B, wherein the reagent A comprises the following raw materials by weight: 12-16 parts of ethylenediaminetetraacetic acid, 6-9 parts of 1-hydroxyethylidene-1,1-diphosphonic acid, and 10-14 parts of sodium citrate, and the reagent B comprises the following raw materials by weight: 15-18 parts of a hydrochloric acid solution, 4-7 parts of sodium acetate, 2-5 parts of thiourea, and 5-8 parts of a methyl violet solution. The invention further discloses a preparation method and a use method of the rapid detection reagent. According to the present invention, the rapid detection reagent has advantages of convenient use, high accuracy, no requirement of large-scale precise instrument and rapid detection, can roughly determine the approximate range of the heavy metal lead content through simple visual inspection, and can meet the on-site rapid detection of food, water samples, and other samples.