The invention discloses a digestion method for hydrogen peroxide in space. A biological zymolase preparation is sprayed to generate aerosol, and the atomized aerosol diffuses and suspends in a required digestion space or sealed space in a particle form, and digests gaseous state or dry fog state hydrogen peroxide in the closed environment by means of Brownian movement. According to the invention, the atomized biological zymolase preparation is sprayed into the to-be-digested space or sealed space through a digestion device, can quickly reduce the concentration of hydrogen peroxide residue in the closed environment, and no harmful substance is generated. Therefore, the method recovers the environmental utilization efficiency, reduces the harm to people health and environment, saves electricity and gas, and reduces energy consumption. The method provided by the invention is practical and simple, and is effective in digestion of hydrogen peroxide. The device used by the invention has simple structure and brings convenience for quick connection.