The invention discloses a method for preparing homopiperazine by utilizing ethyl trifluoroacetate. The method comprises the following steps: (1) taking ethylenediamine as an initial raw material; enabling the ethylenediamine to react with the ethyl trifluoroacetate under the action of an organic solvent, so as to prepare bistrifluoroacetylethylenediamine; (2) enabling the bistrifluoroacetylethylenediamine obtained by the step (1) to react with a 1,3-disubstituted propane compound under the action of a solvent and a catalyst, so as to obtain bistrifluoroacetyl homopiperazine; (3) enabling the bistrifluoroacetyl homopiperazine obtained by the step (2) to react with a hydrogen chloride ethanol solution to obtain homopiperazine bihydrochloride; recycling the ethyl trifluoroacetate; (4) enabling the homopiperazine bihydrochloride obtained by the step (3) to react with alkali under the action of a solvent and a catalyst, so as to prepare the homopiperazine. The method disclosed by the invention has the beneficial effects of simplicity and convenience for operation, relatively low cost, relatively high yield, relatively small pollution and wide applicable range, and can meet the requirements on industrial production of products.