The invention discloses a manufacturing method for a noctilucent valve for a fire extinguisher and belongs to the technical field of fire extinguishers. The manufacturing method comprises the steps that firstly, nylon 66 slices, long glass fiber, silicon carbide, talcum powder and mica powder are uniformly mixed; secondly, the mixed raw materials are melted and then are quickly injected into a die cavity under the high pressure with the help of the thrust of a screw; and die opening is performed after cooling and curing, and an initially-formed ejector rod and an initially-formed valve body are immersed into water at the temperature of 5-20 DEG C and cooled; thirdly, after the formed ejector rod and the formed valve body product are inspected, high-temperature cooking is performed; and fourthly, four passes of paint spraying are conducted on a pressing handle and a lifting handle, white primer is sprayed in the first pass of paint spraying, red paint is sprayed in the second pass of paint spraying, mixed oil paint containing noctilucent powder is sprayed in the third pass of paint spraying, and gloss paint is sprayed in the fourth pass of paint spraying; and ultraviolet light irradiation is conducted on the pressing handle and the lifting handle after paint spraying is completed. The ejector rod and the valve body can completely meet the requirements of the internal environment of the valve for the fire extinguisher on the corrosion resistance, high-pressure resistance and high-low-temperature resistance, the noctilucent valve can emit light for a long time at dark, and a remarkable identification effect is played.