The invention discloses a coke oven four locomotive wireless communication system based on interlocking computer control. The coke oven four locomotive wireless communication system comprises a central control chamber, a communication module electrically connected with the central control chamber, a plurality of bus switching modules electrically connected with the communication module, wireless transmitting modules electrically connected with the bus switching modules, wireless receiving modules used for wireless communication with the wireless transmitting modules, serial port switching modules electrically connected with the wireless receiving modules, locomotives connected with the serial port switching modules, PC adapters electrically connected with the locomotives, and touch screens electrically connected with the PC adapters. The coke oven four locomotive wireless communication system based on the interlocking computer control is advantageous in that the central control chamber is used to transmit the data required to be packaged, and is used to transmit the packaged data by the communication interface of the communication module; 485 communication signals are converted into RS232 signals after passing by the serial port switching modules, and the data is transmitted by the wireless transmitting modules; the safety of the operation of the system is guaranteed.