The invention discloses a dinitrogen amide hydrazone pyridine derivative and a synthesis method and application thereof. The synthesis method of the derivative comprises the following steps of dissolving amide hydrazone pyridine and a catalyst in ethyl alcohol or tetrahydrofuran to obtain liquid A, dissolving camphorquinone in ethyl alcohol or tetrahydrofuran to obtain liquid B, dropwise adding the liquid B into the liquid A, performing stirring for reflux reaction in an inert gas atmosphere, and treating reaction liquid to obtain a target compound (3) after reaction. The synthesized dinitrogen amide hydrazone pyridine derivative is a new compound, is moderate in reaction conditions and has higher extraction performance of simulating palladium in acid high-level radioactive liquid waste.